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Respiratory Cryoablation Solutions

Clinical Pain Points – Thermal Ablation

Risk of airway fire

  • Uncontrollable depth of thermal injury, risk of perforation and cartilage damage

  • Thermal stimulation induces new scar formation, resulting in a pronounced cycle of re-stenosis

  • Incomplete coverage of flat, diffuse granulation tissue and widespread stenoses

  • Clinical Pain Points – Conventional Rigid Single-Point Cryoprobe Ablation

  • Single-point freezing results in small ablation area, extremely low efficiency in treating stenoses

  • Insufficiently low temperatures limit ablation efficacy



Clinical Pain Points Thermal Ablation
Clinical Pain Points Thermal Ablation

Clinical Pain Points – Mechanical Resection

  • Significant trauma, high risk of airway tearing and massive bleeding

  • Severe intraoperative irritation leading to airway spasm

  • Incomplete lesion removal, high recurrence rate


Solutions – Addressing Mechanical Resection Pain Points

  • Flexible balloon catheter delivers low-temperature cryoablation without rigid tearing

  • Mild cold stimulation reduces airway smooth muscle spasm

  • Broad, uniform freezing ensures complete lesion inactivation, reducing recurrence

  • Solutions – Addressing Thermal Ablation Pain Points

  • Pure cryotherapy, no electrical current or open flame, eliminating the risk of airway fire

  • Controllable ablation margins prevent airway perforation and thermal cartilage damage

  • No high-temperature burns to normal mucosa, minimizing new scar formation

  • Adapts to the circumferential airway, providing complete coverage of flat and diffuse granulation stenoses

  • Solutions – Addressing Rigid Single-Point Cryoprobe Pain Points

  • Balloon-based single-session large-area ablation delivers higher procedural efficiency

  • Liquid nitrogen at –196°C ultra-low temperature ensures more thorough inactivation of scar and granulation tissue


Addressing Mechanical Resection Pain Points

Indications for Use

  • Primarily intended for minimally invasive ablation of a wide range of chronic pulmonary diseases and airway conditions, including airway wall lesions, airway tumors, and strictures. It may also be applied to targeted tissues such as the vagus nerve


Core Advantage

  • Cryogenic Efficiency– Liquid nitrogen enables significantly lower working temperatures, delivering strong ablative effect on pathological tissues and substantially improving procedural efficiency.

  • Broad Ablation Coverage– The balloon-based cryotherapy provides a large contact area, reducing overall procedure time.

  • Adjustable Ablation Depth– The depth of cryoablation can be precisely controlled, allowing targeted treatment of airway walls, tumors, vagus nerves, or other tissues as required.

  • High Safety Profile– The high-vacuum insulation design prevents unintended freezing of surrounding tissues or instruments.

  • Comprehensive Size Range– Available in a variety of cryoprobe sizes to accommodate different airway dimensions and lesion types.

  • All-in-One Platform for Multiple Techniques– A single system supports both balloon-based cryotherapy and spray cryotherapy, offering versatile solutions to meet diverse clinical needs.


Clinical Value

  • The Airway Cryoablation System is built on liquid nitrogen-based ultra-low temperature cryoablation technology. Its cryogenic ablation causes minimal damage to airway cartilage, results in limited intraoperative bleeding, and reduces the risk of postoperative scar-induced stenosis. It serves as a core minimally invasive device for interventional pulmonology in the treatment of airway lesions. Its clinical value is concentrated in four dimensions: safe ablation, airway preservation, multi-disease applicability, and improved cost-effectiveness.


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